What are sea cucumbers?
Sea cucumber is a marine organism belonging to the phylum Enchinodermata, which also includes sea urchin and sea star. Recently, sea cucumber has increased in popularity from nutritionists and researchers due to the potential health benefits and nutrients that sea cucumber gives, especially in the research of chronic inflammatory diseases. Many regions around the world use sea cucumber in traditional food and as medicines. Most sea cucumber extracts are still being researched for their anti-inflammatory functions, immunostimulatory properties, and for cancer prevention and treatment.
About this site
This website is an aggregator of sea cucumber research from around the world, providing hyperlinks only to published studies to aid in individual research. The website does not endorse the contents of the research articles, nor validate any claims. It is up to the reader to do their own research into each study’s methodology and published summaries.
This site does not advertise, nor accept solicitations to advertise. If you find a published article specific to sea cucumber that you would like us to add, please submit a link for review through our contact form.
Research Links
- 11/10/2011: High-Value Components and Bioactives from Sea Cucumbers for Functional Foods—A Review
- 13/07/2020: Purification, structural characterization and anticoagulant activities of four sulfated polysaccharides from sea cucumber Holothuria fuscopunctata
- 03/08/2011: High-Value Components and Bioactives from Sea Cucumbers for Functional Foods—A Review
- 11/02/2020: The anticancer activities of stichoposide D isolated from the sea cucumber Stichopus chloronotus on NTERA-2 cancer stem cells
- 12/05/2015: Sea Cucumbers Metabolites as Potent Anti-Cancer Agents – Marine Drugs
- 01/08/2013: Frondoside A Suppressive Effects on Lung Cancer Survival, Tumor Growth, Angiogenesis, Invasion, and Metastasis
- 15/07/2011: Frondoside A inhibits breast cancer metastasis and antagonizes prostaglandin E receptors EP4 and EP2
- 01/01/2010: Chemopreventive Effects of Frondanol A5, a Cucumaria frondosa Extract, against Rat Colon Carcinogenesis and Inhibition of Human Colon Cancer Cell Growth
- 01/01/2016: In Vivo Anti-Cancer Mechanism of Low-Molecular-Weight Fucosylated Chondroitin Sulfate (LFCS) from Sea Cucumber Cucumaria frondosa
- 18/09/2017: Mechanisms of cancer cell killing by sea cucumber-derived compounds
- 24/07/2014: Cytotoxic and Apoptosis-Inducing Activity of Triterpene Glycosides from Holothuria scabra and Cucumaria frondosa against HepG2 Cells
- 04/2020 – Biological Activity of Some Natural Components of Marine Sea Cucumber and Orange Peel
- 29/03/2017: Effects of Cucumaria frondosa against melanoma cell cancer
- 01/07/2010: Anti-Pancreatic Cancer Effects of a Polar Extract From the Edible Sea Cucumber, Cucumaria frondosa
- 19/05/2020: Sea cucumber Cucumaria frondosa fucoidan inhibits osteosarcoma adhesion and migration by regulating cytoskeleton remodeling
- 02/05/2018: Pharmacological Potent of Sea Cucumbers
- 17/10/2017: Sea Cucumber Glycosides: Chemical Structures, Producing Species and Important Biological Properties
- 10/10/2011: High-Value Components and Bioactives from Sea Cucumbers for Functional Foods—A Review
- 01/10/2013: Sulphated polysaccharide from the sea cucumber Cucumaria frondosa affect maturation of human dendritic cells and their activation of allogeneic CD4(+) T cells in vitro
- 01/05/2017: Immunomodulatory and Antiproliferative Effects of Cucumaria frondosa Against Murine Melanoma Cell Line B16-F10 In-Vitro
- 01/05/2015: In vitro antiviral activities of enzymatic hydrolysates extracted from byproducts of the Atlantic holothurian Cucumaria frondosa
- 2009: Immunnostimulatory activity of Holothuria atra sea cucumber
- 2006: Immunomodulatory properties of Cumaside
- 01/12/2010: Immunomodulatory Action of Monosulfated Triterpene Glycosides from the Sea Cucumber Cucumaria okhotensis: Stimulation of Activity of Mouse Peritoneal Macrophages
- 01/11/2017: Cucumarioside A2-2 Causes Macrophage Activation in Mouse Spleen
- 11/14/2019: Preparation of Antioxidant Peptide by Microwave- Assisted Hydrolysis of Collagen and Its Protective Effect Against H2O2-Induced Damage of RAW264.7 Cells
- 12/24/2019: Antioxidant and anti-melanogenic activities of ultrasonic extract from Stichopus japonicus
- 01/01/14: The protective effect of eicosapentaenoic acid-enriched phospholipids from sea cucumber Cucumaria frondosa on oxidative stress in PC12 cells and SAMP8 mice
- 01/01/17: Rapid modulation of lipid metabolism in C57BL/6J mice induced by eicosapentaenoic acid-enriched phospholipid from Cucumaria frondosa
- 04/2020 – Biological Activity of Some Natural Components of Marine Sea Cucumber and Orange Peel
- 26/10/2020 – Characterization of a Coproduct from the Sea Cucumber Cucumaria frondosa and Its Effects on Visceral Adipocyte Size in Male Wistar Rats